Research areas

  1. Published

    Affinity and translocation relationships via hPEPT1 of H-Xaa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs

    Omkvist, D. H., Trangbæk, D. J., Mildon, J., Paine, J. S., Larsen, Birger Brodin, Begtrup, M. & Nielsen, C. U., 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 2, p. 327-331

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1)

    Omkvist, D. H., Larsen, S. B., Nielsen, C. U., Steffansen, B., Olsen, L., Jørgensen, Flemming Steen & Larsen, Birger Brodin, 2010, In: The AAPS Journal. 12, 3, p. 385-396

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen

    Omkvist, D. H., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: British Journal of Pharmacology. 161, 8, p. 1793-1805

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Ibuprofen is an inhibitor of hPEPT1: Implications for drug-drug interactions at the level of drug absorption

    Omkvist, D. H., Larsen, Birger Brodin & Nielsen, C. U., 2010.

    Research output: Contribution to conferencePosterResearch

  5. Published

    Intestinal drug delivery via hPEPT1 : in vitro and in silico evaluation of the realtionship between substrate, binding and translocation

    Omkvist, D. H., Feb 2011, Det Farmaceutiske Fakultet. 51 p.

    Research output: Book/ReportPh.D. thesisResearch

  6. Published

    Constituents in kava extracts potentially involved in hepatotoxicity: A review

    Olsen, L. R., Grillo, M. P. & Skonberg, C., 2011, In: Chemical Research in Toxicology. 24, p. 992-1002

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Prediction of activation energies for hydrogen abstraction by cytochrome p450

    Olsen, L., Rydberg, P., Rod, T. H. & Ryde, U., 2006, In: Journal of Medicinal Chemistry. 49, 22, p. 6489-6499

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hvad har varme at gøre med lægemidler?

    Olsen, L., Kasper, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Jørgensen, Flemming Steen, 2006, In: Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Cytochrome P450 Mediated Drug Metabolism

    Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection

    Olsen, K., Hansen, S. H., Sidenius, U. & Schmiegelow, Kjeld, 2008, In: Journal of Chromatography - B. 864, 1-2, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme a thioester intermediate in rats

    Olsen, J., Li, C., Skonberg, C., Bjørnsdottir, I., Sidenius, U., Benet, L. Z. & Hansen, S. H., 2007, In: Drug Metabolism and Disposition. 35, 5, p. 758-764

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Toltrazuril and its two main metabolites in the environment - Analytical development

    Olsen, J., Hansen, M., Krogh, K. A., Bak, S. A., Brandt, A. & Björklund, E., 2011.

    Research output: Contribution to conferencePosterResearch

  13. Published

    Isolation of the MAO-inhibitor naringenin from Mentha aquatica L

    Olsen, H. T., Stafford, G. I., van Staden, J., Christensen, Søren Brøgger & Jäger, A. K., 2008, In: Journal of Ethnopharmacology. 117, 3, p. 500-502

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Peptoid-Peptide hybrid backbone architectures

    Olsen, Christian Adam, 25 Jan 2010, In: ChemBioChem. 11, 2, p. 152-160

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Antimicrobial, hemolytic, and cytotoxic activities of ß-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs

    Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: ChemBioChem. 11, 10, p. 1356-1360

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Small molecules from spiders used as chemical probes

    Olsen, C. A., Kristensen, Anders Skov & Strømgaard, Kristian, 25 Nov 2011, In: Angewandte Chemie International Edition. 50, 48, p. 11296-11311

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Solid-phase synthesis of neuroactive spider-wasp hybrid toxin analogues using a backbone amide linker

    Olsen, Christian Adam, Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Tetrahedron Letters. 48, 3, p. 405-408

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Aziridines in parallel- and solid-phase synthesis

    Olsen, Christian Adam, Bonke, G., Vedel, L., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: European Journal of Organic Chemistry. 2007, 11, p. 1717-1724

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Solid-phase peptide synthesis and circular dichroism study of chiral ß-peptoid homooligomers

    Olsen, Christian Adam, Lambert, M., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2008, In: Amino Acids. 34, 3, p. 465-471

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    α-Peptide/ß-Peptoid Chimeras

    Olsen, Christian Adam, Bonke, G., Vedel, L., Adsersen, A., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Organic Letters. 9, 8, p. 1549–1552 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Hyraceum, the fossilized metabolic product of rock hyraxes (Procavia capensis), shows GABA-benzodiazepine receptor affinity

    Olsen, A., Prinsloo, L. C., Scott, L. & Jäger, A. K., 2008, In: South African Journal of Science. 103, 11/12, p. 437-438

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Translational pain research: evaluating analgesic effect in experimental visceral pain models

    Olesen, A. E., Andresen, T., Christrup, Lona Louring & Upton, R. N., 2009, In: World Journal of Gastroenterology. 15, 2, p. 177-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

    Olesen, A. E., Jarvig, L., Hansen, O. B., Højsted, J., von Holstein-Rathlou, Niels-Henrik, Jonsson, T., Sjøgren, P., Sonne, N. M., Sørensen, J. T. & Christrup, Lona Louring, 2007, In: Ugeskrift for læger. 169, 21, p. 2024-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A pharmacokinetic and pharmacodynamic study of oral oxycodone in a human experimental pain model of hyperalgesia

    Olesen, A. E., Upton, R., Staahl, C., Christrup, Lona Louring, Arendt-Nielsen, L. & Drewes, A. M., 2010, In: Clinical Pharmacokinetics. 49, 12, p. 817-827

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment

    Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.

    Research output: Contribution to conferencePosterResearch