Research areas

  1. Published

    Using a phylogenetic approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe Galantheae

    Mellergaard Larsen, M., Adsersen, A., Davis, A. P., Lledó, M. D., Jäger, A. K. & Rønsted, Nina, Oct 2010, In: Biochemical Systematics and Ecology. 38, 5, p. 1026-1034

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Resistance and re-organization of an eccosystem in response to biological invasion: Some hypotheses

    Marchi, M., Jørgensen, S. E., Bécares, E., Corsi, I., Marchettini, N. & Bastianoni, S., 2011, In: Ecological Modelling. 222, 16, p. 2992-3001

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Modelling the carbon cycle of Siena province (Tuscany, central Italy)

    Marchi, M., Jørgensen, S. E., Pulselli, F. M., Marchettini, N. & Bastianoni, S., 2012, In: Ecological Modelling. 225, p. 40-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Dynamic model of Lake Chozas (León, NW Spain) - Decrease in eco-exergy from clear to turbid phase due to introduction of excotic crayfish

    Marchi, M., Jørgensen, S. E., Bécares, E., Corsi, I., Marchettini, N. & Bastianoni, S., 2011, In: Ecological Modelling. 222, 16, p. 3002-3010

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Novel non-injectable formulation approaches of peptides and proteins

    Mao, S., Cun, D. & Kawashima, Y., 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). 1 ed. Chichester: Wiley, p. 29-57

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  6. Published

    Building the quality into pellet manufacturing environment - Feasibility study and validation of an in-line quantitative near infrared (NIR) method

    Mantanus, J., Ziémons, E., Rozet, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, Jukka & Hubert, P., 2010, In: Talanta: The International Journal of Pure and Applied Analytical Chemistry. 83, 2, p. 305-311

    Research output: Contribution to journalJournal articleResearch

  7. Published

    Ribavirin dosage in patients with HCV genotypes 2 and 3 who completed short therapy with peg-interferon alpha-2b and ribavirin

    Mangia, A., Dalgard, O., Minerva, N., Verbaan, H., Bacca, D., Larsen, H. R., Copetti, M., Caretta, V., Piazzollla, V., Cozzolongo, R., Mottola, L. & Andriulli, A., 1 Jun 2010, In: Alimentary Pharmacology and Therapeutics. 31, 12, p. 1346-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Investigation of thermodynamic properties in an ecological model developing from ordered to chaotic states

    Mandal, S., Ray, S., Roy, S. & Jørgensen, S. E., 2007, In: Ecological Modelling. 204, 1-2, p. 40-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S., van de Weert, Marco & Grohganz, Holger, 2011, In: A A P S PharmSciTech. 12, 2, p. 627-635

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Analysis of insulin allostery in solution and solid state with FTIR

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2009, In: Journal of Pharmaceutical Sciences. 98, 9, p. 3265-3277

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Quality by design: Spray drying of insulin intended for inhalation

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 828-838

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Drying methods for protein pharmaceuticals

    Maltesen, M. J. & van de Weert, Marco, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 81-88

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Contribution of South African plants to medicinal plant biotechnology

    Makunga, N. P., Jäger, A. K. & van Staden, J., 2008, In: South African Journal of Botany. 2, p. 372

    Research output: Contribution to journalConference abstract in journalResearch

  14. Published

    Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump

    Mahmmoud, Y. A. & Christensen, Søren Brøgger, Oct 2011, In: BBA General Subjects. 1808, 10, p. 2413-2420

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic

    Maher, S., Leonard, T. W., Jacobsen, Jette & Brayden, D. J., 2009, In: Advanced Drug Delivery Reviews. p. 1427-1449

    Research output: Contribution to journalReviewResearch

  16. Published

    Excitability changes related to GABAA receptor plasticity during pregnancy

    Maguire, J., Ferando, I., Simonsen, C. M. & Mody, I., 2009, In: Journal of Neuroscience. 29, 30, p. 9592-9601

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effects of cannabinoid CB(1) receptor agonism and antagonism on SKF81297-induced dyskinesia and haloperidol-induced dystonia in Cebus apella monkeys

    Madsen, M. V., Peacock, L. P., Werge, Thomas, Andersen, M. H. & Andreasen T., Jesper, 2011, In: Neuropharmacology. 60, 2-3, p. 418-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Development of personal desiderata while learning GIS

    Madsen, Lene Møller, Christiansen, Frederik Voetmann & Rump, Camilla Østerberg, 2009, Frontiers in Science Education Research: Proceedings of the Frontiers in Science Education Research Conference 22 - 24 March 2009, Famagusta, North Cyprus. Bisel, A. & Garib, M. U. (eds.). Eastern Mediterranean University Press, p. 441-450 9 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  19. Published

    Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism

    Madsen, K. G., Olsen, J., Skonberg, C., Hansen, S. H. & Jurva, U., 2007, In: Chemical Research in Toxicology. 20, 5, p. 821-831

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bioactivation of diclofenac in vitro and in vivo: correlation to electrochemical studies

    Madsen, K. G., Skonberg, C., Jurva, U., Cornett, Claus, Hansen, S. H., Johansen, Tommy Nørskov & Olsen, J., 2008, In: Chemical Research in Toxicology. 21, 5, p. 1107-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Functional characterization of GABA transporters: Emphasis on betaine-GABA transporter 1 and its role in seizure management

    Madsen, K. K., 2009, København: Museum Tusculanum. 54 p.

    Research output: Book/ReportPh.D. thesis

  22. Published

    Pharmacological manipulation of extrasynaptic GABA transporters: implications for epilepsy management

    Madsen, K. K., Ebert, B., Larsson, O. M., Clausen, Rasmus Prætorius, Schousboe, Arne & White, H. S., 2008, In: Epilepsia. Suppl. 7, p. 347

    Research output: Contribution to journalConference abstract in journalResearch

  23. Published

    GABA transporter localization to lipid raft membrane microdomains in neurons and astrocytes

    Madsen, K. K., Pickering, Darryl S, Hansen, G. H., Danielsen, E. M., Larsson, O. M. & Schousboe, Arne, 2007, In: Journal of Neurochemistry. 102, s1, p. 46

    Research output: Contribution to journalConference abstract in journalResearch

  24. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol

    Madsen, K. K., Ebert, B., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 1 Jul 2011, In: Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 214-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    GABA-transportører: håb om bedre epilepsibehandling

    Madsen, K. K., Clausen, Rasmus Prætorius, Larsson, O. M. & Schousboe, Arne, 2008, In: Lægemiddelforskning. p. 22-24

    Research output: Contribution to journalJournal articleCommunication

  26. Published

    Regulation of excitation by GABA neurotransmission: Focus on metabolism and transport

    Madsen, K. K., Larsson, O. M. & Schousboe, Arne, 2008, In: Results and Problems in Cell Differentiation. 44, p. 201-221

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs

    Madsen, K. K., White, H. S. & Schousboe, Arne, 2010, In: Pharmacology & Therapeutics. 125, 3, p. 394-401

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Functional and pharmacological aspects of GABA transporters

    Madsen, K., White, H. S., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O. M., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2007, Handbook of nerochemistry and molecular neurobiology: Neural membranes and transport. Lajtha, A. & Reith, M. E. A. (eds.). 3rd. ed. Berlin: Springer, Vol. 3. p. 285-304

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    In Vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum

    Madsen, H. B., Ifversen, P., Madsen, F., Larsen, Birger Brodin, Hausser, I. & Nielsen, Hanne Mørck, 2009, In: The AAPS Journal. 11, 4, p. 728-739

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Farvel til sprøjten: udvikling af vaccineplaster med nanopartikler

    Madsen, H. B., Ifversen, P., Madsen, F., Manniche, S. & Nielsen, Hanne Mørck, 2007, In: Lægemiddelforskning. p. 12-13

    Research output: Contribution to journalJournal articleCommunication

  31. Published

    Investigation of the interaction between modified ISCOMs and stratum corneum lipid model systems

    Madsen, H. B., Arboe-Andersen, H. M., Rozlosnik, N., Madsen, F., Ifversen, P., Kasimova, M. R. & Nielsen, Hanne Mørck, 2010, In: Biochimica et Biophysica Acta - Biomembranes. 1798, p. 1779-1789

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Penetration and interaction of ISCOM nanoparticles with the skin

    Madsen, H. B., 2010, København: Museum Tusculanum. 73 p.

    Research output: Book/ReportPh.D. thesis

  33. Published

    Synthesis of imidazole-4(5)-acetic acid analogues: for characterizing the ionotropic GABA receptors

    Madsen, C., 2010, København: Det Farmaceutiske Fakultet. 186 p.

    Research output: Book/ReportPh.D. thesis

  34. Published

    5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acidC receptor agonists

    Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, 17, p. 4147-4161

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Characterization of the metabolic syndrome in a selectivity bred polygenetic rat model mimicking human obesity

    Madsen, A. N., 2007, København: Faculty of Pharmaceutical Sciences, University of Copenhagen. 133 p.

    Research output: Book/ReportPh.D. thesis

  36. Published

    Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Antioxidant activity and phenylpropanoids of Phlomis lychnitis L. A traditional herbal tea

    López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y. & Calvo, M. I., 2010, In: Plant Foods for Human Nutrition. 65, 2, p. 179-185

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain)

    López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y. & Calvo, M. I., 12 Apr 2011, In: Journal of Ethnopharmacology. 134, 3, p. 1014-1017

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Neuroprotective and neurological properties of Melissa officinalis

    López, V., Martín, S., Gómez-Serranillos, M. P., Carretero, M. E., Jäger, A. K. & Calvo, M. I., 2009, In: Neurochemical Research. 34, 11, p. 1955-1961

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Neuroprotective and neurochemical properties of mint extracts

    López, V., Martín, S., Gómez-Serranillos, M. P., Carretero, M. E., Jäger, A. K. & Calvo, M. I., 2010, In: Phytotherapy Research. 24, 6, p. 869-874

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    GMP - three letters with many interpretations:  Protection of patients or killing the clinical and research applications of PET?

    Långström, B. & Honoré, P. G. H., 2008, In: European Journal of Nuclear Medicine and Molecular Imaging. 35, 4, p. 693-694

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The risk of exaggerated risk aversion-: a life and death struggle for molecular imaging

    Långström, B., Grahnen, A., Honoré, P. H., Borlak, J., Bergstrom, M., Nielsen, B., Vanderheyden, J., Watanabe, Y., Josephsson, R., Høilund-Carlsen, P. F., Schwaiger, M., Larson, S. M., Goldenberg, D. M., Melzer, A., Engler, H., Hicks, R., Sundin, A., Seppänen, M., Hedenstierna, G., Nordberg, A. & 1 others, Brooks, D., 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 10, p. 1693-4 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Isolation and structural elucidation of tiamulin metabolites formed in liver microsomes of pigs

    Lykkeberg, A. K., Cornett, Claus, Halling-Sørensen, B. & Hansen, S. H., 2006, In: Journal of Pharmaceutical and Biomedical Analysis. 42, 2, p. 223-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Susceptibility of bacteria isolated from pigs to tiamulin and enrofloxacin metabolites

    Lykkeberg, A. K., Halling-Sørensen, B. & Jensen, L. B., 2007, In: Veterinary Microbiology. 121, 1-2, p. 116-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Chemical approaches to improving bioavailability properties of oral drug candidates

    Luthman, K. & Steffansen, B., 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. Steffansen, B., Brodin, B. & Uhd Nielsen, C. (eds.). Pharmaceutical Press, p. 71-98

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  46. Published

    Investigation of the selenium metabolism in cancer cell lines

    Lunøe, K., Gabel-Jensen, C., Stürup, Stefan, Andresen, Lars, Skov, Søren & Gammelgaard, Bente, 2011, In: Metallomics. 3, 2, p. 162-168 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A method for analysis of dimethyl selenide and dimethyl diselenide by LC-ICP-DRC-MS

    Lunøe, K., Skov, S., Gabel-Jensen, C., Stürup, Stefan & Gammelgaard, Bente, 2010, In: Analytical and Bioanalytical Chemistry. 398, 7-8, p. 3081-3086

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Internal correction of spectral interferences and mass bias for selenium metabolism studies using enriched stabel isotopes in combination with multiple linear regression

    Lunøe, K., Martinez-Sierra, J. G., Gammelgaard, Bente & Alonso, J. I. G., 2012, In: Analytical and Bioanalytical Chemistry. 402, 9, p. 2749-2763

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Kombination af konserveringsmidler i cremer nedsætter risikoen for allergi

    Lundov, M. D. & Moesby, L., 2009, In: Lægemiddelforskning. p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  50. Published

    Contamination versus preservation of cosmetics: a review on legislation, usage, infections, and contact allergy

    Lundov, M. D., Moesby, L., Zachariae, Claus & Johansen, Jeanne Duus, 2009, In: Contact Dermatitis. 60, 2, p. 70-8

    Research output: Contribution to journalReviewResearch

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