Research areas

  1. Published

    Hypoglemic activity of Iraqi Rheum ribes root extract

    Naqishbandi, A. M., Josefsen, K., Pedersen, M. E. & Jäger, A. K., 2009, In: Pharmaceutical Biology. 47, 5, p. 380-383

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Alkaloids from Boophone disticha with affinity to the serotonin transporter

    Neergaard, J. S., Andersen, J., Pedersen, M. E., Stafford, G. I., van Staden, J. & Jäger, A. K., 2009, In: South African Journal of Botany. 75, 2, p. 371-374

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

    Nelson, J. K., Frølund, S. U., Tikhonov, D. B., Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 17, p. 3087-3091

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study

    Nielsen, E. I., Sandström, M., Honoré, P. H., Ewald, U. & Friberg, L. E., 2009, In: Clinical Pharmacokinetics. 48, 4, p. 253-63 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Development of an N-O linker for fluorous phase chemistry & fluorous parallel synthesis of a piperazinedione fused tricyclic compound library

    Nielsen, S. D., 2009, København: Det Farmaceutiske Fakultet. 161 p.

    Research output: Book/ReportPh.D. thesis

  6. Published
  7. Published

    Thermodynamic constraints of life as downward causation in ecosystems

    Nielsen, S. N., 2009, In: Cybernetics & Human Knowing - A Journal of Second Order Cybernetics, Autopoiesis and Cyber-Semiotics. 16, p. 27-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Understanding the functional principles of nature - proposing another type of ecosystem services

    Nielsen, S. N. & Müller, F., 2009, In: Ecological Modelling. 220, p. 1913-1925

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Innovativt nanopartikeldesign bag skræddersyede vacciner

    Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Lægemiddelforskning. p. 19-21

    Research output: Contribution to journalJournal articleResearch

  10. Published

    Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators

    Nordly, P. J., Madsen, H. B., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Expert Opinion on Drug Delivery. 6, 7, p. 1-16

    Research output: Contribution to journalReviewResearch

  11. Published

    Critical evaluation of the FANTOM3 non-coding RNA transcripts

    Nordström, K. J. V., Mirza, M. A. I., Almén, M. S., Gloriam, David E., Fredriksson, R. & Schiöth, H. B., 2009, In: Genomics. 94, 3, p. 169-176

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment

    Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.

    Research output: Contribution to conferencePosterResearch

  13. Published

    Translational pain research: evaluating analgesic effect in experimental visceral pain models

    Olesen, A. E., Andresen, T., Christrup, Lona Louring & Upton, R. N., 2009, In: World Journal of Gastroenterology. 15, 2, p. 177-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

    Ottesen, L. K., Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2009, In: Chemistry: A European Journal. 15, 12, p. 2966-2978

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A comparison of the effects of P-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE)

    Ouyang, H., Andersen, T. E., Chen, W., Nofsinger, R., Steffansen, B. & Borchardt, R. T., 2009, In: Journal of Pharmaceutical Sciences. 98, 6, p. 2227-2236

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Factors that restrict intestinal cell permeation of cyclic prodrugs of an opioid peptide (DADLE): Part II. Role of metabolic enzymes in the intestinal mucosa

    Ouyang, H., Chen, W., Andersen, T. E., Steffansen, B. & Borchardt, R. T., 2009, In: Journal of Pharmaceutical Sciences. 98, 1, p. 349-361

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Factors that restrict the intestinal cell permeation of cyclic prodrugs of an opioid peptide (DADLE): Part I. Role of efflux transporters in the intestinal mucosa

    Ouyang, H., Chen, W., Andersen, T. E., Steffansen, B. & Borchardt, R. T., 2009, In: Journal of Pharmaceutical Sciences. 98, 1, p. 337-348

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A concise route to branched erythrono-gamma-lactones. Synthesis of the leaf-closing substance potassium (+/-)-(2R,3R)-2,3,4-trihydroxy-2-methylbutanoate

    Pedersen, D. S., Robinson, T. V., Taylor, D. K. & Tiekink, E. R. T., 2009, In: Journal of Organic Chemistry. 74, 11, p. 4400-4403

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Amides from Piper capense with CNS activity: a preliminary SAR analysis

    Pedersen, M. E., Metzler, B., Stafford, G. I., van Staden, J., Jäger, A. K. & Rasmussen, H. B., 2009, In: Molecules. 14, 9, p. 3833-3843

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Dynamics of adipose tissue metabolism - effects of pharmacological intervention

    Pedersen, S. M. F., 2009, Copenhagen: Museum Tusculanum. 85 p.

    Research output: Book/ReportPh.D. thesis

  21. Published

    Effect of synthetic and natural phospholipids on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D activity

    Petersen, G., Pedersen, A. H., Pickering, Darryl S, Begtrup, M. & Hansen, Harald S., 2009, In: Chemistry and Physics of Lipids. 162, 1-2, p. 53-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Drop-to-drop microextraction across a supported liquid membrane by an electrical field under stagnant conditions

    Petersen, Nickolaj J., Jensen, H., Hansen, S. H., Rasmussen, K. E. & Pedersen-Bjergaard, Stig, 2009, In: Journal of Chromatography A. 1216, 9, p. 1496-1502

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques

    Poongavanam, V., Taboureau, O., Oostenbrink, C., Vermeulen, N. P. E., Olsen, L. & Jørgensen, Flemming Steen, 2009, In: Drug Metabolism and Disposition. 37, 3, p. 658-664

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands

    Poongavanam, V., Hritz, J., Taboureau, O., Olsen, L., Jørgensen, Flemming Steen, Vermeulen, N. P. E. & Oostenbrink, C., 2009, In: Journal of Chemical Information and Modeling. 49, 1, p. 43-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers

    Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In: Biochemistry. 48, p. 9313-9320

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Near-infrared chemical imaging in formulation development of solid dosage forms

    Ravn, C., 2009, Det Farmaceutiske Fakultet. 93 p.

    Research output: Book/ReportPh.D. thesis

  27. Published

    Carbohydrate recognition in water and combinatorial methods utilizing encoded beads for finding Avidin ligands

    Reenberg, T. K., 2009, København: Museum Tusculanum. 97 p.

    Research output: Book/ReportPh.D. thesis

  28. Published

    Modified diet in renal disease method overestimates renal function in selected elerdly patients

    Roberts, G. W., Ibsen, P. M. & Schiøler, C. T., 2009, In: Age and Ageing. 38, p. 698-703

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Dihydroxylation of 4-substituted 1,2-dioxines: a concise route to branched erythro sugars

    Robinson, T. V., Pedersen, D. S., Taylor, D. K. & Tiekink, E. R. T., 2009, In: Journal of Organic Chemistry. 74, 14, p. 5093-5096

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Fast prediction of cytochrome P450 mediated drug metabolism

    Rydberg, P. Å. A., Poongavanam, V., Oostenbrink, C. & Olsen, L., 2009, In: ChemMedChem. 4, 12, p. 2070-2079

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The accuracy of geometries for iron porphyrin complexes from density functional theory

    Rydberg, P. Å. A. & Olsen, L., 2009, In: Journal of Physical Chemistry A. 113, 43, p. 11949-11953

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull

    Saaby, Lasse, Rasmussen, H. B. & Jäger, A. K., 2009, In: Journal of Ethnopharmacology. 121, 1, p. 178-181

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Gamma-aminobutyric acid (GABA)

    Schousboe, Arne & Waagepetersen, Helle S., 2009, Encyclopedia of neuroscience. Squire, L. R. (ed.). Academic Press, Vol. 4. p. 511-515

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  34. Published

    Glial modulation of excitability via glutamate and GABA transporters

    Schousboe, Arne & White, H. S., 2009, Encyclopedia of basic epilepsy research. Schwartzkroin, P. A. (ed.). Academic Press, Vol. 1. p. 397-401

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  35. Published

    Synthesis of bicyclic acidic amino acids conformationally restricted mimetics of Glu or Asp & work towards the enantioselective total synthesis of cardinalin 3

    Sejberg, J. J. P., 2009, København: Det Farmaceutiske Fakultet. 169 p.

    Research output: Book/ReportPh.D. thesis

  36. Published

    Functional significance of brain glycogen in sustaining glutamatergic neurotransmission

    Sickmann, H. M., Walls, Anne Byriel, Schousboe, Arne, Bouman, S. D. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 80-86 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Glutamatergic neurotransmission under physiological and diabetic conditions - involvement of brain glycogen

    Sickmann, H. M., 2009, København: Det Farmaceutiske Fakultet. 81 p.

    Research output: Book/ReportPh.D. thesis

  38. Published

    Metabolic profiles of the brains of Zucker Diabetic Fatty, Zucker Obese and Sprague-Dawley rats and the involvement of glycogen metabolism

    Sickmann, H. M., Bouman, S. D., Schousboe, Arne, Tracey, W. R. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 293-293

    Research output: Contribution to journalConference abstract in journalResearch

  39. Published

    Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors

    Sivaprakasam, M., Hansen, K. B., David, O., Nielsen, Birgitte, Traynelis, S. F., Clausen, Rasmus Prætorius, Couty, F. & Bunch, Lennart, 2009, In: ChemMedChem. 4, 1, p. 110-117

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    GAD65 is essential for the maintenance of GABA homeostasis

    Smeland, O., Walls, A. B., Eyolfsson, E. M., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2009, In: Journal of Neurochemistry. p. 51-51

    Research output: Contribution to journalConference abstract in journalResearch

  41. Published

    Drug-related problems identified in medication reviews by Australian pharmacists

    Stafford, A. C., Tenni, P. C., Peterson, G. M., Jackson, S. L., Hejlesen, A., Villesen, C. & Rasmussen, M., 2009, In: Pharmacy World and Science. 31, 2, p. 216-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    African psychoactive plants

    Stafford, G. I., Jäger, A. K. & van Staden, J., 2009, African natural plant products: New discoveries and challenges in chemistry and quality. Juliana, H. R., Simon, J. E. & Ho, C-T. (eds.). Washington DC: American Chemical Society, Vol. 1021. p. 323-346 (ACS symposium series 1021, Vol. 1021).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  43. Published

    Simulating permeability and drug absorption

    Steffansen, B. & Rapin, N. P. J., 2009.

    Research output: Contribution to conferencePosterResearch

  44. Published

    Skræddersyede proteiner: uden naturens begrænsninger

    Strømgaard, Kristian, Jensen, M. S. & Kristensen, Anders Skov, 2009, In: Lægemiddelforskning. p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  45. Published

    Sparing the ortho-position in nucleophilic aromatic substitution-specific displacement of the 4-SePh group in 2,4-bis(phenylseleno)nitrobenzene

    Stuhr-Hansen, N., Götze, T. F., Henriksen, L., Sølling, Theis Ivan, Langkilde, Annette Eva & Sørensen, H. O., 2009, In: Heteroatom Chemistry. 20, 2, p. 101-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Protecting ecosystem health: facing the challange of a blobally changing environment: Organic farming practices strongly influence the PAH degradation potential of agricultural soil

    Styrishave, Bjarne, Johnsen, A. R., Magid, J., Aamand, J. & Halling-Sørensen, B., 2009.

    Research output: Contribution to conferencePosterResearch

  47. Published

    Risk assessment of contaminants in sewage sludge applied on Norwegian soils: opinion of the panel on contaminants in the Norwegian Scientific Committee for Food Safety

    Sundstøl Eriksen, G., Amundsen, C. E., Bernhoft, A., Eggen, T., Grave, K., Halling-Sørensen, B., Källqvist, T., Sogn, T. & Sverdrup, L., 2009, Oslo: Norwegian Scientific Committee for Food Safety. 208 p.

    Research output: Book/ReportReport

  48. Published

    Biological recognition and interactions of liposomes: Liposome triggering of innate immune responses: A perspective on benefits and adverse reactions

    Szebeni, J. & Moghimi, S. M., 2009, In: Journal of Liposome Research. 19, 2, p. 85-90

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands

    Szymanska, E., Pickering, Darryl S, Nielsen, Birgitte & Johansen, Tommy Nørskov, 2009, In: Bioorganic & Medicinal Chemistry. 17, 17, p. 6390-401 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    1,4-Bis(4-chlorophenylseleno)-2,5-dimethoxybenzene

    Sørensen, H. O. & Stuhr-Hansen, N., 2009, In: Acta Crystallographica. Section E: Structure Reports Online. 65, 1, p. o13 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review