Peirce`s semiotics is eminently open because it is truly general. Library and Information Science can benefit from the application of Peirce`s semiotics offering a (meta) analytical framework to define its central concepts and to compare, otherwise not comparable, concepts within diverse sub-fields of LIS. We endow the concept of information with semiotic characteristics and point toward how sign classes can help making initial observations concerning theoretical shortcomings within LIS.