Psychiatric comorbidity: A concept in need of a theory
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Psychiatric comorbidity : A concept in need of a theory. / Nordgaard, Julie ; Nielsen, Kasper Møller; Rasmussen, Andreas Christian Rosén; Henriksen, Mads Gram.
In: Psychological Medicine, Vol. 53, 2023, p. 5902–5908.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Psychiatric comorbidity
T2 - A concept in need of a theory
AU - Nordgaard, Julie
AU - Nielsen, Kasper Møller
AU - Rasmussen, Andreas Christian Rosén
AU - Henriksen, Mads Gram
PY - 2023
Y1 - 2023
N2 - Despite being a relatively new concept, psychiatric comorbidity, i.e. the co-occurrence of two or more mental disorders, has become widespread in clinical practice and psychiatric research. In this article, we trace the origin of the concept of psychiatric comorbidity, discuss the conceptual literature and point to basic problems concerning inadequate definition of the concept, differential diagnostic issues, and reification of mental disorders. We illustrate how these problems may have consequences for diagnostic assessment in current clinical practice and psychiatric research. To address some of the problems related to psychiatric comorbidity, we discuss potential principles for assessing psychiatric comorbidity. Inspired by Feinstein's original concept of comorbidity in general medicine and his differential diagnostic principles, we emphasize the importance of independence of mental disorders when assessing psychiatric comorbidity. We suggest that knowledge of trait v. state conditions and of the multitudinous clinical manifestations beyond what is captured in the diagnostic manuals may be helpful for assessing the independence of mental disorders and thus psychiatric comorbidity. We further argue that a more hierarchical diagnostic system and explicit exclusionary rules could improve clinical practice and research by reducing informational complexity and combating unwarranted psychiatric comorbidity.
AB - Despite being a relatively new concept, psychiatric comorbidity, i.e. the co-occurrence of two or more mental disorders, has become widespread in clinical practice and psychiatric research. In this article, we trace the origin of the concept of psychiatric comorbidity, discuss the conceptual literature and point to basic problems concerning inadequate definition of the concept, differential diagnostic issues, and reification of mental disorders. We illustrate how these problems may have consequences for diagnostic assessment in current clinical practice and psychiatric research. To address some of the problems related to psychiatric comorbidity, we discuss potential principles for assessing psychiatric comorbidity. Inspired by Feinstein's original concept of comorbidity in general medicine and his differential diagnostic principles, we emphasize the importance of independence of mental disorders when assessing psychiatric comorbidity. We suggest that knowledge of trait v. state conditions and of the multitudinous clinical manifestations beyond what is captured in the diagnostic manuals may be helpful for assessing the independence of mental disorders and thus psychiatric comorbidity. We further argue that a more hierarchical diagnostic system and explicit exclusionary rules could improve clinical practice and research by reducing informational complexity and combating unwarranted psychiatric comorbidity.
U2 - 10.1017/S0033291723001605
DO - 10.1017/S0033291723001605
M3 - Review
C2 - 37264812
VL - 53
SP - 5902
EP - 5908
JO - Psychological Medicine
JF - Psychological Medicine
SN - 0033-2917
ER -
ID: 347402129